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Nobel Prize awarded for discovery of optogenetics technique

The 2026 Nobel Prize in Physiology or Medicine was jointly awarded to Karl Deisseroth of Stanford University in the United States, Peter Hegemann of Humboldt University in Berlin, and Georg Nagel of the University of Würzburg in Germany. They were recognised for their discoveries of light-gated ion channels and the development of optogenetics, a technique that uses light to control specific neurons. Since its development in the mid-2000s, optogenetics has become one of the most important tools in neuroscience research.

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Optogenetics is a technique that allows researchers to use light to switch specific neurons on or off. This gives scientists a powerful tool to study how individual brain cells and neural circuits influence behaviour. The method is based on the discovery of light-sensitive proteins called channelrhodopsins, which have become fundamental to modern neuroscience.

The award recognises decades of foundational research by all three scientists. Peter Hegemann and Georg Nagel identified the light-gated ion channels in algae that form the basis of the technique. Karl Deisseroth was essential in adapting this discovery into a practical tool that could be used to control neurons in living animals. Since then, the technique has been applied to research on various brain conditions, including Parkinson's disease, depression and addiction, helping scientists understand the neural mechanisms underlying these disorders.

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