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Nobel Prize in Medicine Recognises Optogenetics Breakthrough

Karl Deisseroth, Peter Hegemann and Georg Nagel have been awarded the 2026 Nobel Prize in Physiology or Medicine for their discoveries of light-gated ion channels and the development of optogenetics. This technique enables researchers to control neuronal activity using light, fundamentally transforming neuroscience research.

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The 2026 Nobel Prize in Physiology or Medicine has been awarded jointly to Karl Deisseroth of Stanford University in the United States, and German biophysicists Peter Hegemann of Humboldt University and Georg Nagel of the University of Würzburg for their work on light-gated ion channels and the development of optogenetics.

Optogenetics is a technique that allows scientists to control the activity of specific neurons using light. Since its development, it has become one of the most widely used methods in neuroscience research. Researchers can now activate or deactivate individual brain cells and immediately observe the effects on behaviour and brain function. This precision has provided unprecedented insights into how the brain works.

The discoveries underlying optogenetics have had a significant impact on experimental biology beyond neuroscience alone. The technique has opened new possibilities for understanding neurological and psychiatric conditions, and it continues to drive advances in our knowledge of the brain.

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